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Serotonin, a neurotransmitter (the chemical messengers your nervous system relies on to regulate various bodily functions), may be at least partly responsible for premature ejaculation (PE). Serotonin influences brain cells involved with mood, sleep, memory, appetite, and sexual desire.
· Generally speaking, high levels of serotonin (either administered directly into the brain, or as the result of genetic absence of the transporter), inhibit sexual behavior.
but did you know it's also prescribed to treat premature ejaculation?. Sertraline is an antidepressant that's part of the selective serotonin reuptake. With a 50mg dose, the men's mean ejaculatory interval increased to 13.1 minutes.. The stop- start strategy is exactly what it sounds like-during sex, when.
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This drug is known for its high specificity and selectivity for the SERT  .. Relation between blood vitamin B12 levels with premature ejaculation: Case- control study. Some subtypes (5-HT1a) reduce ejaculatory latency, and other subtypes.
Over the past 20-30 years, the premature ejaculation (PE) treatment paradigm, reduce performance anxiety, and modify his maladaptive sexual scripts.. These drugs block axonal reuptake of serotonin from the synaptic cleft of central. administration of an SSRI, increased synaptic 5-HT levels are downregulated by .
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· Premature (early) ejaculation-also referred to as rapid ejaculation-is the most common type of sexual dysfunction in men younger than 40 years. An occasional instance of premature ejaculation might not be cause for concern, but, if the problem occurs with more than 50% of attempted sexual relations, a dysfunctional pattern usually exists for.
An occasional instance of premature ejaculation might not be cause for. Topical anesthetics may reduce penile sensitivity and excitability and delay ejaculation.. the increased synaptic content of serotonin and norepinephrine at the level of.
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The inhibitory effect of serotonin on libido, ejaculation, and orgasm. premature ejaculation have marked high serum leptin levels compared to controls, been reported to reduce plasma leptin levels in rats  and it has been noted that leptin .
When serotonin is injected into some parts of the rat brain, it causes a delay in ejaculation. In other areas of the brain, it causes ejaculation to take place. Dopamine also plays a role in ejaculation, although its role has not been as thoroughly explored as that of serotonin.
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